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KMID : 0882420100790010072
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Korean Journal of Medicine
2010 Volume.79 No. 1 p.72 ~ p.76
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A case of Castleman’s disease patient treated successfully with cyclic high-dose steroid therapy
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Cho Sung-Won
Choi Jong-Soo
Chung Hyoung-Jung
Oh Ho-Suk
Kang Gil-Hyun
Kim Su-Hee
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Abstract
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Castleman’s disease is rare, and its cause is unknown. Although various treatments have been attempted, no standard treatment has been established for it. A 51-year-old male on hemodialysis with end-stage renal disease was admitted to our hospital with fever and myalgia. He was diagnosed with multicentric Castleman’s disease (MCD) of the hyaline vascular type. Considering his underlying disease and general condition, cyclic high-dose steroid therapy (prednisolone 1 mg/kg/day for 5 days) was administered every 4 weeks, eight times in total. After this, no symptomatic manifestations of MCD or signs on computed tomography were observed. We report an immunocompromised patient diagnosed with MCD of the hyaline vascular type, who was successfully treated with cyclic high-dose steroid therapy.
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KEYWORD
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Castleman’s disease, Lymphoproliferative disorder, ESRD, Prednisolone
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